RECRUITING: Cognition during trofinetide treatment – USA

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Status: RecruitingProject: Cognitive function in Rett syndrome during trofinetide treatment
Registry number: NCT06705816
Location: University of Minnesota / Gillette Children’s Rett clinic
Participants: People with Rett syndrome who are beginning prescribed trofinetide through the associated clinic

What is being studied?
This observational study uses remote eye tracking and other non-invasive measurements to examine attention, eye movement, learning and autonomic function before and after trofinetide treatment. The researchers are looking for measures that can capture cognitive changes without relying on speech or extensive motor responses.

Contact: Breanne Byiers — +1 612 626 7892 — byier001@umn.edu
Official study record: https://clinicaltrials.gov/study/NCT06705816

Information checked 3 September 2026. This project observes care prescribed by the clinical team; it does not advise starting trofinetide. Treatment decisions belong with the person’s clinician.